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Important
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Catherin
Schein's
-Faculty
Homepage
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Homepage
Computational
Biology Homepage
Department of
Biochemistry and
Molecular Biology
Werner
Braun's
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Department of
Microbiology & Immunology
Sealy Center for
Structural Biology and Molecular Biophysics
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(74) Chen, D., Misra, M., Sower,
L., Peterson, J.W., Kellogg, G.E. and Schein, C.H. (2008)
Novel
inhibitors of Anthrax edema factor.
Bioorg. Med. Chem., (in
press).
(73) Oezguen, N., Zhou, B., Negi, S.S.,
Ivanciuc, O., Schein, C.H., Labesse, G. and Braun, W. (2008)
Comprehensive
3D-modeling of allergenic proteins and amino acid composition of
potential conformational IgE epitopes.
Mol. Immunol., (in press).
(72)
Cummins, S.F., Xie, F., de
Vries, M.R., Annangudi, S.P., Misra, M., Degnan, B.M., Sweedler, J.V.,
Nagle, G.T., Schein, C.H. (2007)
 Aplysia
temptin: the "glue" in the water-borne attractin pheromone complex.
Febs J., 274(20), 5425-5437.
(71) Negi, S., Schein, C.H.,
Oezguen, N., Power, T.D. and Braun, W. (2007)
InterProSurf:
a web server for predicting interacting sites on protein surfaces.
Bioinformatics, 23(24), 3397-3399.
(70) Misra, M. and Schein,
C.H. (2007)
Flavitrack:
An annotated database of flavivirus sequences.
Bioinformatics, 23(19), 2645-2647.
(69) Sha, J., Wang, S.F., Suarez,
G., Sierra, J.C., Fadl, A.A., Erova, T.E., Foltz, S.M., Khajanchi,
B.K., Silver, A., Graf, J., Schein, C.H., Chopra, A.K. (2007)
Further
characterization of a type III secretion system (T3SS) and of a new
effector protein from a clinical isolate of Aeromonas hydrophila-Part I.
Microb. Pathog., 43(4), 127-146.
(68) Oezguen, N., Schein, C.H.,
Peddi, S.R., Power, T.D., Izumi, T. and Braun, W. (2007)
A
"moving metal mechanism" for substrate cleavage by the DNA repair
endonuclease APE-1.
Proteins, 68(1), 313-323.
(67)
Chen, D., Menche, G, Power,
T.D., Peterson, J.W. and Schein, C.H . (2007)
Accounting
for ligand-bound metal ions in docking small molecules on adenylyl
cyclase toxins.
Proteins, 67(3), 593-605.
(66) Schein, C.H. Ivanciuc O. and
Braun, W. (2007)
Bioinformatics
approaches to classifying allergens and predicting cross-reactivity.
Immunol. Allergy
Clin.
North Am., 27(1), 1-27.
(65) Cummins, S.F., Xie, F., Misra,
M., Amare, A., Jakubowski, J.A., de Vries, M.R., Sweedler, J.V., Nagle,
G.T. and Schein, C.H. (2007)
Recombinant
production and structural studies of the aplysia water-borne protein
phermone enticin indicates it has a novel disulfide stabilized fold.
Peptides,
28(1), 94-102.
(64) Schein, C.H., Ivanciuc,
O.and Braun, W. (2006)
Structural
Database of Allergenic Proteins (SDAP).
Food Allergy, Edited by S.J. Maleki, copyright 2006
ASM Press, Washington D.C. 257-283.
(63) Negi, S.S., Kolokoltsov, A.A.,
Schein, C.H., Davey, R.A. and Braun, W. (2006)
Determining
functionally important amino acid residues of the E1 protein of
Venezuelan equine encephalitis visus.
J. Mol. Model.,
12(6), 921-929.
(62) Schein, C.H., Oezguen, N.,
Volk, D.E., Garimella, R., Paul, A. and Braun, W. (2006)
NMR
structure of the viral peptide linked to the genome (VPg) of poliovirus.
Peptides, 27(7), 1676-1684..
(61) Schein, C.H., Volk, D.E.,
Oezguen, N. and Paul, A. (2006)
Novel,
structure-based mechanism for uridylylation of the genome-linked
peptide (VPg) of picornaviruses.
Proteins, 63(4), 719-726.
(60) Cummins S.F., Nichols A.E.,
Schein C.H. and Nagle G.T. (2006)
Newly
identified water-borne protein pheromones interact with attractin to
stimulate mate attraction in Aplysia.
Peptides,
27(3), 597-606.
(59) Midoro-Horiuti, T., Schein, C.H.,
Mathura, V., Braun, W.,
Czerwinski, E.W., Togawa, A., Kondo, Y., Oka, T., Watanabe, M. and
Goldblum, R.M. (2006)
 Structural
basis for epitope sharing between group 1 allergens of cedar pollen.
Mol.
Immunol., 43(6),
509-518.
(58) Schein, C.H.,
Ivanciuc, O. and Braun, W. (2005)
Common
physical-chemical properties correlate with similar structure of the
IgE epitopes of peanut allergens.
J.
Agric. Food Chem.,
53(22), 8752-8759.
(57)
Schein, C.H., Zhou, B. and Braun,
W. (2005)
(56) Cummins, S.F., Schein, C.H., Xu, Y.,
Braun, W. and Nagle, G.T.
(2005)
Molluscan attractins, a family of
water-borne protein pheromones with interspecific attractiveness.
Peptides, 26,
121-129.
(55) Schein,
C.H.,
Zhou, B., Oezguen, N., Mathura,
V.S.,
and
Braun, W. (2005)
Molego-based
definition of the architecture and specificity of metal binding sites.
Proteins, 58,
200-210.
(54) Painter,
S.D., Cummins, S.F., Nichols, A.E., Akalal, D.B.G., Schein, C.H.,
Braun, W.,
Smith, J.S., Susswein, A.J., Levy, M., de Boer, P.A.C.M., ter Maat, A.,
Miller, M.W., Scanlan, C., Milberg, R.M., Sweedler, J.V. and
Nagle, G.T. (2004)
Structural
and functional analysis of Aplysa attractins, a family of water-borne
protein phermones with interspecific attractiveness.
Proc.
Natl. Acad. Sci. USA,
101, 6929-6933.
(53) Ivanciuc,
O.,
Oezguen, N., Mathura,
V.S.,
Schein, C.H., Xu, Y. and Braun, W. (2004)
Using
property based sequence motifs and 3D modeling to determine structure
and functional regions of proteins.
Curr.
Med. Chem.,
11, 583-593.
(51) Izumi, T., Schein, C.H., Oezguen,
N., Feng, Y. and Braun, W.
(2004)
Effects
of backbone contacts 3' to the abasic site on the cleavage and the
product binding by human apurinic/apyrimidinic endonuclease (APE1).
Biochemistry, 43, 684-689.
(49) Hermann, P.M.,
Schein, C.H., Nagle, G.T. and Wildering, W.C. (2004)
Lymnaea
EGF and gigantoxin I, novel invertebrate member of the epidermal growth
factor family.
Curr. Pharm. Des.,
10(31):3885-3892.
(48) Akalal, D.B.,
Schein, C.H. and Nagle, G.T. (2004)
Mollusk-derived
growth factor and the new subfamily of adenosine deaminase-related
growth factors.
Curr. Pharm. Des.,
10(31):3893-3900.
(47)
Midoro-Horiuti, T., Mathura,
V., Schein, C.H., Braun, W., Yu, S.,
Watanabe, M., Lee, J.C., Brooks,
E.G. and Goldblum, R. (2003)
Major
linear IgE epitopes of mountain cedar pollen allergen Jun a 1 map to
the pectate lyase catalytic site.
Mol. Immunol.,
40, 555-562.
(46)
Ivanciuc, O., Mathura,
V.,
Midoro-Horiuti, T., Braun, W., Goldblum, R. and Schein, C.H. (2003)
Detecting
potential IgE-reactive sites on food proteins using a sequence and
structure database, SDAP-Food.
J. Agr. Food Chem., 51, 4830-4837.
(45)
Garimella,
R., Xu, Y., Schein, C.H., Rajarathnam, K., Painter, S.D., Nagle, G.T.
and Braun, W. (2003)
NMR
solution structure of attractin, a water-borne protein pheromone from
the mollusk Aplysia californica.
Biochemistry, 42, 9970-9979.
(40) Murtazina,
D., Puchkaev, A.V., Schein, C.H., Oezguen, N., Braun, W., Nanavati, A.
and Pikuleva, I.A. (2002)
Membrane-protein
interactions contribute to efficient 27-hydroxylation of cholesterol by
mitochondrial cytochrome P450 27A1.
J. Biol. Chem., 277, 37582-37589.
(37) Schein, C.H., Nagle, G.T., Page, J.
Sweedler, J.V., Xu, Y.,
Painter, S.D. and Braun, W. (2001)
Aplysia
attractin: biophysical characterization and modeling of a water-borne
pheromone.
Biophys. J., 81, 463-472.
(35) Soman, K.V., Schein, C.H.,
Zhu, H. and Braun, W. (2001)
Homology
modeling and simulations of nuclease structures.
In Nuclease Methods and
Protocols, Schein, C.H. (ed) for series Methods
in Molecular Biology
Vol. 160, 2001, Humana
Press, Totowa, N.J., pp. 263-286.
(34) Midoro-Horiuti,
T M. Goldblum, R M.
Schein, C H. Soman, K V.
Braun, W. Kurosky, A. Brooks, E G. (2000)
Structural
Analysis of Jun a 3, a Potentially Inducible Allergen of Mountain Cedar
Pollen.
J.
Allergy Clin. Immun., 105
(1): Part 2, S327.
(32) Soman, K.V., Midoro-Horiuti, T.,
Ferreon, J.C., Goldblum, R.M.,
Brooks, E.G., Kurosky,
A., Braun, W. and
Schein, C.H. (2000).
Homology
modeling and characterization of Ig E binding epitopes of mountain
cedar allergen Jun a 3.
Biophys.
J., 79,
1601-1609.
(29) Midoro-Horiuti,
T., Goldblum, R.M., Kurosky, A., Wood, T.G., Schein, C.H. and Brooks,
E.G. (1999)
Molecular
cloning of mountain cedar (Juniperus ashei) pollen major allergen, June
a 1.
J. Allergy Clin. Immunol.,
104(3 Pt 1):613-617.
(28) Schein, C.H.
(1999)
Protein
expression, soluble.
For The Encyclopedia of
Bioprocess Technology: Fermentation,
Biocatalysis and Bioseparation.
J. Wiley and Sons, New
York, NY. pp 2156-2169.
(27) Schein, C.H.
(1999)
Protein
aggregation, degradation.
For the
Encyclopedia of
Bioprocess Technology: Fermentation,
Biocatalysis and Bioseparation.
J. Wiley and Sons, New
York, NY. pp 2134-2155.
(22) Boix, E., Nogués, M.V., Schein,
C.H., Benner, S.A. and Cuchillo, C.M. (1994)
Reverse
transphosphorylation by ribonuclease A needs an intact p2 binding
site. Point mutations at Lys-7 and Arg-10 alter the catalytic
properties of the enzyme.
J. Biol. Chem.,
269, 2529-2534.
(18) Schein, C.H., Boix, E., Haugg, M.,
Holliger, K.P., Hemmi, S., Frank, G. and Schwalbe, H. (1992)
Secretion
of mammalian ribonucleases from Escherichia coli using the signal
sequence of murine spleen ribonuclease.
Biochem. J.,
283(Pt 1):137-144.
(16) Schein, C.H.
(1991)
Physical
methods and models for the study of protein aggregation.
In: Protein Refolding
(G. Georgiou, and E. de Bernardez-Clark,
eds) A.C.S. Books
Washington, D.C., pp
21-34.
(9) Palva, I., Lehtovaara, P.,
Kèèrièinen, L., Sibakov, M., Cantell, K., Schein,
C.H., Kashiwagi, K. and Weissmann, C. (1983)
Secretion
of interferon by Bacillus subtilis.
Gene,
22:229-235.
(8) Weissmann, C.,
Nagata, S., Boll, W., Fountoulakis, M., Fujisawa, A., Fujisawa, J.,
Haynes, J., Henco, K., Mantei, N., Ragg, H., Schein, C., Schmid, J.
Shaw, G., Streuli, M., Taira, H., Todokoro, K. and Weidle, U.
(1982)
Structure
and expression of human alpha-interferon genes.
UCLA Symposium on
Molecular and Cellular Biology XXV:295-326.
(7) Weissmann, C.,
Nagata, S., Boll, W., Fountoulakis, M., Fujisawa, A., Fujisawa, J.,
Haynes, J., Henco,K., Mantei, N., Ragg, H., Schein, C., Schmid, J.,
Shaw, G., Streuli, M., Taira, H., Todokoro, K. and Weidle, U.
(1982)
Structure
and expression of human interferon-alpha genes.
Philoso. Trans. R. Soc.
London (Biol.), 299:7-28.
(6) Weissmann, C.,
Weidle, U., Ragg, H., Haynes, J., Mantei, N., Shaw, G., Taira, H.,
Mishima, M., Boll, W., Schein, C. and Fountoulakis, M. (1982)
Expression
of interferon genes in a heterospecific environment.
In Humoral Factors
in Host Defense, Takeda Science Foundation on
Bioscience.
(5) Weissmann, C.,
Nagata, S., Boll, W., Fountoulakis, M., Fujisawa, A., Fujisawa, J.,
Haynes, J., Henco, K., Mantei, N., Ragg, H., Schein, C., Schmid, J.
Shaw, G., Streuli, M., Taira, H., Todokoro, K. and Weidle, U.
(1982)
Structure
and function of human alpha-interferon genes.
International Symposium
for the Princess Takamatsu Cancer Research Fund
12:1-22.
(4) Schellekens, H.,
deReus, A., Bolhuis, R., Fountoulakis, M., Schein, C., Ecsödi, J.,
Nagata, S. and Weissmann, C. (1981)
Comparative
antiviral efficiency of leukocyte and bacterially produced human
alpha-interferon in rhesus monkeys.
Nature,
292:775-776.
This site last updated
on 24 June 2008 by David Power.
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